First dual AK/GSK-3β inhibitors endowed with antioxidant properties as multifunctional, potential neuroprotective agents.
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DOI: 10.1016/j.ejmech.2017.06.017
Abstract: The manuscript deals with the design, synthesis and biological evaluation of novel benzoxazinone-based and indole-based compounds as multifunctional neuroprotective agents. These compounds inhibit human adenosine kinase (hAK) and human glycogen synthase kinase 3 beta (hGSK-3β)… read more here.
Keywords: first dual; endowed antioxidant; dual gsk; gsk inhibitors ... See more keywords