PPAR&agr;/CB1 receptor dual ligands as a novel therapy for alcohol use disorder: Evaluation of a novel oleic acid conjugate in preclinical rat models
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical Pharmacology"
DOI: 10.1016/j.bcp.2018.09.008
Abstract: Graphical abstract Figure. No Caption available. ABSTRACT Recent studies have demonstrated the utility of drugs modulating the endogenous cannabinoid system to control excessive alcohol intake. Among them, drugs interacting with acylethanolamide receptors including cannabinoid CB1… read more here.
Keywords: ppar agr; cb1 receptor; receptor; dual ligands ... See more keywords
Can dual-ligand targeting enhance cellular uptake of nanoparticles?
Sign Up to like & getrecommendations! Published in 2017 at "Nanoscale"
DOI: 10.1039/c7nr01020f
Abstract: Dual ligand targeting to different types of over-expressed receptors on cell surfaces is a promising strategy in nanomedicine. Here, by using dissipative particle dynamics simulations, the effect of the surface distribution and physicochemical properties of… read more here.
Keywords: ligand targeting; dual ligand; uptake nanoparticles; dual ligands ... See more keywords