A Dual‐Locked Tandem Fluorescent Probe for Imaging of Pyroptosis in Cancer Chemo‐Immunotherapy
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Materials"
DOI: 10.1002/adma.202206510
Abstract: Real‐time imaging of programmed cancer cell death (PCD) is imperative to monitor cancer therapeutic efficacy and tailor therapeutic regimens; however, specific in vivo detection of intratumoral pyroptosis remains challenging. Herein, a dual‐locked and tandem activatable… read more here.
Keywords: pyroptosis cancer; pyroptosis; cancer chemo; cancer ... See more keywords
Noncovalent Dual-Locked Near-Infrared Fluorescent Probe for Precise Imaging of Tumor via Hypoxia/Glutathione Activation.
Sign Up to like & getrecommendations! Published in 2022 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.2c00406
Abstract: Stimulus-responsive fluorescent probes have broad applications in the early detection and treatment of tumors and thus promote the personalized treatment of tumors and improve patient survival. Among the repertoires of probes, dual-locked near-infrared (NIR) fluorescent… read more here.
Keywords: locked near; near infrared; fluorescent; tumor ... See more keywords
Synergistically activated dual-locked fluorescent probes to monitor H2S-induced DNA damage.
Sign Up to like & getrecommendations! Published in 2022 at "Chemical communications"
DOI: 10.1039/d2cc04247a
Abstract: Naphthalimide-based fluorescent probes (NAN0-N3 and NAN6-N3) were developed with dual locked fluorescence. Here, ≥1.9 × 10-2 mM of H2S and ≥2.2 × 10-2 μg mL-1 of DNA could unlock a highly sensitive off-on fluorescence response… read more here.
Keywords: damage; dna damage; h2s induced; fluorescent probes ... See more keywords