Dual mechanisms ensure a gradient of cortical PAR-1 for C. elegans embryonic polarization
Sign Up to like & getrecommendations! Published in 2017 at "Mechanisms of Development"
DOI: 10.1016/j.mod.2017.04.214
Abstract: The cell nucleus is a highly organized environment containing various nuclear bodies or organelles that are involved in the metabolism of RNA. A few nuclear structures are known to associate with specific chromosomal loci to… read more here.
Keywords: chromosome four; cortical par; mechanisms ensure; gradient cortical ... See more keywords
Dual Mechanisms of Raffinose in Attenuating Alcoholic Liver Injury: Gut Microbiota Modulation and Microbiota-Independent Bile Acid Pool Reprogramming.
Sign Up to like & getrecommendations! Published in 2025 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.5c09907
Abstract: Alcohol-related liver disease (ALD) poses a growing global health burden, yet current therapies remain limited. Here, we demonstrate that raffinose, a naturally occurring oligosaccharide, alleviates ALD through dual mechanisms involving gut microbiota modulation and microbiota-independent… read more here.
Keywords: gut microbiota; gut; bile acid; dual mechanisms ... See more keywords
Dual Mechanisms of Action of a Halogenated Allyl Fatty Acid against Methicillin-Resistant Staphylococcus aureus
Sign Up to like & getrecommendations! Published in 2025 at "ACS Omega"
DOI: 10.1021/acsomega.5c07162
Abstract: Antimicrobial resistance in MRSA demands agents with new mechanisms. We evaluated two synthetic unsaturated fatty acids, 2-hexadecynoic acid (2-HDA) and (Z)-2-allyl-3-bromo-2-hexadecenoic acid (DAT-51), across clinical and reference MRSA strains. Both compounds reduced the viability in… read more here.
Keywords: mechanisms action; dat; dual mechanisms; action halogenated ... See more keywords
Dual mechanisms of digestion-resistant proteins in food systems: structural resistance and enzyme inhibition.
Sign Up to like & getrecommendations! Published in 2025 at "Critical reviews in food science and nutrition"
DOI: 10.1080/10408398.2025.2551784
Abstract: Digestion-resistant proteins, which are proteins that reduce or inhibit the digestive process of dietary nutrients, might be an emerging field to explore. Growing public interest in food composition and health has drawn attention to digestion-resistant… read more here.
Keywords: food; resistance; digestion resistant; dual mechanisms ... See more keywords
With guselkumab, does the dual mechanisms to inhibit IL-23, help in ulcerative colitis?
Sign Up to like & getrecommendations! Published in 2025 at "Expert Opinion on Biological Therapy"
DOI: 10.1080/14712598.2025.2508836
Abstract: ABSTRACT Introduction Ulcerative colitis (UC) includes a dysregulated immune response. The conventional therapy includes immunosuppressants, and biologics targeting inflammatory mediators, but these are often inadequate, or subjects become unable to tolerate them. Areas covered QUASAR:… read more here.
Keywords: guselkumab; guselkumab dual; dual mechanisms; ulcerative colitis ... See more keywords
Dual Mechanisms of Coniferyl Alcohol in Phenylpropanoid Pathway Regulation
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.896540
Abstract: Lignin is a complex phenolic polymer that imparts cell wall strength, facilitates water transport and functions as a physical barrier to pathogens in all vascular plants. Lignin biosynthesis is a carbon-consuming, non-reversible process, which requires… read more here.
Keywords: coniferyl alcohol; dual mechanisms; mechanisms coniferyl; regulation ... See more keywords
Dual Mechanisms of the Diazepine-Benzimidazole Derivative, DAB-19, in Modulating Glutamatergic Neurotransmission
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms26115299
Abstract: The search for novel compounds with anticonvulsant properties remains a key focus in neuropharmacology. Recently, the diazepine-benzimidazole derivative, DAB-19, has emerged as a promising candidate due to its demonstrated anxiolytic and analgesic effects. In this… read more here.
Keywords: dab; benzimidazole derivative; dual mechanisms; derivative dab ... See more keywords