Dual-molecular barcode sequencing detects rare variants in tumor and cell free DNA in plasma
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-60361-3
Abstract: Conventional next generation sequencing analysis has provided important insights into cancer genetics. However, the detection of rare (low allele fraction) variants remains difficult because of the error-prone nucleotide changes derived from sequencing/PCR errors. To eliminate… read more here.
Keywords: dna; barcode; molecular barcode; barcode sequencing ... See more keywords
A chemically encoded timer for dual molecular delivery at tailored ranges and concentrations.
Sign Up to like & getrecommendations! Published in 2018 at "Chemical communications"
DOI: 10.1039/c8cc03253j
Abstract: Spatiotemporal control of molecular distribution is much in demand in many fields of chemistry. To address this goal, we exploit a low molecular weight branched self-immolative architecture, which acts as a triggerable chemically encoded timer… read more here.
Keywords: chemically encoded; encoded timer; molecular delivery; dual molecular ... See more keywords