Computational Design and Biological Evaluation of Analogs of Lupin Peptide P5 Endowed with Dual PCSK9/HMG-CoAR Inhibiting Activity
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DOI: 10.3390/pharmaceutics14030665
Abstract: (1) Background: Proprotein convertase subtilisin/kexin 9 (PCSK9) is responsible for the degradation of the hepatic low-density lipoprotein receptor (LDLR), which regulates the circulating cholesterol level. In this field, we discovered natural peptides derived from lupin… read more here.
Keywords: hmg coar; activity; dual pcsk9; pcsk9 ... See more keywords