Discovery of novel dual PPARα/δ agonists based on benzimidazole scaffold for the treatment of non-alcoholic fatty liver disease.
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DOI: 10.1016/j.bioorg.2020.103803
Abstract: Many peroxisome proliferator-activated receptors (PPARs) agonists have been developed for the treatment of metabolic disorders, while several PPARs agonists were discontinued in clinical trials because of PPARγ related side effects. In order to increase the… read more here.
Keywords: ppar; non alcoholic; dual ppar; treatment ... See more keywords