Monitoring In Vivo Performances of Protein-Drug Conjugates Using Site-Selective Dual Radiolabeling and Ex Vivo Digital Imaging.
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DOI: 10.1021/acs.jmedchem.2c00401
Abstract: In preclinical models, the development and optimization of protein-drug conjugates require accurate determination of the plasma and tissue profiles of both the protein and its conjugated drug. To this aim, we developed a bioanalytical strategy… read more here.
Keywords: drug conjugates; radiolabeling vivo; dual radiolabeling; drug ... See more keywords