Abstract 4108: Longitudinal diffusion-weighted MRI assessment of NRAS mutant melanoma response to dual RAF-MEK inhibition reveals differences associated with collagen deposition
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DOI: 10.1158/1538-7445.am2018-4108
Abstract: Background and Purpose: Oncogenic NRAS, which drives the constitutive activation of the RAS-RAF-MEK-ERK pathway, is expressed in 15–20% of melanomas and is the second most common driver mutation in this disease. Inhibition of oncogenic RAS… read more here.
Keywords: nras mutant; diffusion; diffusion weighted; dual raf ... See more keywords