Emergence and Genomic Characterization of Neisseria gonorrhoeae Isolates with High Levels of Ceftriaxone and Azithromycin Resistance in Guangdong, China, from 2016 to 2019
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DOI: 10.1128/spectrum.01570-22
Abstract: Here, we report five sporadic dual-resistant isolates, including FC428-related ceftriaxone-resistant clones with MICs of ≥0.5 mg/L and high-level azithromycin resistance with MICs of ≥1,024 mg/L. This study highlights that dual-resistant clones with the same evolutionary origin as… read more here.
Keywords: guangdong china; resistant clones; fc428 related; resistance ... See more keywords
P664 In vitro evaluation of gepotidacin, an oral antimicrobial against multidrug-resistant mycoplasma genitalium
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DOI: 10.1136/sextrans-2019-sti.731
Abstract: Background Mycoplasma genitalium has rapidly developed resistance to first-line azithromycin and second-line moxifloxacin. Third-line pristinamycin is difficult to source and only 80% effective. Consequently, there is an urgent need for alternative therapies, and to protect… read more here.
Keywords: macrolide; mycoplasma genitalium; dual resistant; resistance ... See more keywords