pH/Ultrasound Dual‐Responsive Gas Generator for Ultrasound Imaging‐Guided Therapeutic Inertial Cavitation and Sonodynamic Therapy
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DOI: 10.1002/adhm.201700957
Abstract: Herein, a pH/ultrasound dual-responsive gas generator is reported, which is based on mesoporous calcium carbonate (MCC) nanoparticles by loading sonosensitizer (hematoporphyrin monomethyl ether (HMME)) and modifying surface hyaluronic acid (HA). After pinpointing tumor regions with… read more here.
Keywords: cavitation; dual responsive; ultrasound dual; responsive gas ... See more keywords
Diselenide‐Based Dual‐Responsive Prodrug as Pyroptosis Inducer Potentiates Cancer Immunotherapy
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DOI: 10.1002/adhm.202202135
Abstract: Pyroptosis is demonstrated to trigger antitumor immunity and represents a promising new strategy to potentiate cancer immunotherapy. The number of potent pyroptosis inducers, however, is limited and without tumor‐targeting capability, which inevitably causes damage in… read more here.
Keywords: dual responsive; pyroptosis; dse poc; cancer immunotherapy ... See more keywords
Dual‐Responsive Nanocomposites for Synergistic Antibacterial Therapies Facilitating Bacteria‐Infected Wound Healing
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DOI: 10.1002/adhm.202202652
Abstract: The rising dangers of bacterial infections have created an urgent need for the development of a new generation of antibacterial technologies and therapeutics. Antibacterial photodynamic therapy (PDT), considered as a noninvasive treatment with no drug… read more here.
Keywords: synergistic antibacterial; responsive nanocomposites; tio2; antibacterial therapies ... See more keywords
A Dual‐Responsive Magnetoactive and Electro–Ionic Soft Actuator Derived from a Nickel‐Based Metal–Organic Framework
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DOI: 10.1002/adma.202203613
Abstract: There is growing demand for multiresponsive soft actuators for the realization of natural, safe, and complex motions in robotic interactions. In particular, soft actuators simultaneously stimulated by electrical and magnetic fields are always under development… read more here.
Keywords: nickel based; metal organic; magnetoactive electro; based metal ... See more keywords
A Dual‐Responsive STAT3 Inhibitor Nanoprodrug Combined with Oncolytic Virus Elicits Synergistic Antitumor Immune Responses by Igniting Pyroptosis
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DOI: 10.1002/adma.202209379
Abstract: Immune checkpoint blockade (ICB) therapy shows excellent efficacy against malignancies; however, insufficient tumor immunogenicity and the immunosuppressive tumor microenvironment (TME) are considered as the two major stumbling blocks to a broad ICB response. Here, a… read more here.
Keywords: antitumor immune; pyroptosis; combined oncolytic; dual responsive ... See more keywords
Dual-responsive pegylated polypeptoids with tunable cloud point temperatures.
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DOI: 10.1002/bip.23243
Abstract: A series of pegylated polypeptoids have been readily synthesized by a strategy combining ring-opening polymerization (ROP) and thiol-yne photoaddition. The polypeptoids simultaneously incorporated branched oligo(ethylene glycol) (OEG) units and thioether bonds in the side-chains. All… read more here.
Keywords: tunable cloud; pegylated polypeptoids; dual responsive; responsive pegylated ... See more keywords
Dual Responsive Molecular-Arm Modified Single Enzyme Molecules for Efficient Cellulose Hydrolysis.
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DOI: 10.1002/marc.202200092
Abstract: Immobilizing cellulase for improving its hydrolysis activity and recyclability is critical for a cost-effective and environment-friendly conversion of cellulosic biomass. However, developing a strategy for achieving a high mass-transfer rate and good separation efficiency between… read more here.
Keywords: cellulase; dual responsive; single enzyme; efficiency ... See more keywords
A Dual-Responsive Artificial Skin for Tactile and Touchless Interfaces.
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DOI: 10.1002/smll.202206830
Abstract: The progress from intelligent interactions and supplemented/augmented reality requires artificial skins to shift from the single-functional tactile paradigm. Dual-responsive sensors that can both detect pre-contact proximal events and tactile pressure levels enrich the perception dimensions… read more here.
Keywords: dual responsive; responsive artificial; artificial skin; skin tactile ... See more keywords
Acid/light dual-responsive biodegradable polymeric nanocarriers for efficient intracellular drug delivery
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DOI: 10.1007/s00289-018-2470-3
Abstract: A novel amphiphilic acid/light dual-cleavable diblock copolymer poly(ε-caprolactone)-acetal-nitrobenzyl ester-poly(ethylene glycol) (PCL-PEG) was prepared via the ring-opening polymerization of ε-caprolactone using 5-propargylether-2-nitrobenzyl alcohol as the initiator and subsequent “click” coupling reaction with azide-terminated poly(ethylene glycol) containing… read more here.
Keywords: acid light; dual responsive; light dual; drug ... See more keywords
NIR- and UV-dual responsive amphiphilic copolymer micelles with light-dissociable PAG-side groups
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DOI: 10.1007/s00396-017-4013-0
Abstract: Amphiphilic random copolymer micelle of P(NVP-co-NHPM) that responds to both UV and NIR light was designed and investigated. N-hydroxyphthalimide methacrylate—bearing a photoacid generator functional group was synthesized and used to construct the hydrophobic segment of… read more here.
Keywords: nir light; dual responsive; copolymer; responsive amphiphilic ... See more keywords
Dual pH-responsive “charge-reversal like” gold nanoparticles to enhance tumor retention for chemo-radiotherapy
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DOI: 10.1007/s12274-019-2518-1
Abstract: The strategy of pH-responsive aggregation in tumor micro-environment (TME) provides an intriguing platform for enhancing tumor retention and exerting therapeutic effects sufficiently. In this work, we have designed an intelligent dual pH-responsive self-aggregating nano gold… read more here.
Keywords: chemo radiotherapy; dual responsive; pah dmma; tumor retention ... See more keywords