Generation of Pancreatic Ductal Organoids and Whole‐Mount Immunostaining of Intact Organoids
Sign Up to like & getrecommendations! Published in 2019 at "Current Protocols in Cell Biology"
DOI: 10.1002/cpcb.82
Abstract: Traditionally, studies of cells and tissues have been performed on isolated primary cells or immortalized cell lines by culturing them in 2D culture dishes or flasks. However, a caveat regarding 2D culture is that the… read more here.
Keywords: generation pancreatic; pancreatic ductal; ductal cells; ductal organoids ... See more keywords
Immunohistochemical localization of cannabinoid receptor 1 (CB1) in the submandibular gland of mice under normal conditions and when stimulated by isoproterenol or carbachol.
Sign Up to like & getrecommendations! Published in 2017 at "Archives of oral biology"
DOI: 10.1016/j.archoralbio.2017.05.003
Abstract: OBJECTIVE We wished to investigate the subcellular localization of CB1, a receptor for the endocannabinoids in mouse submandibular glands (SMGs) under normal conditions and when stimulated by adrenergic or cholinergic agonists. MATERIALS AND METHODS SMGs… read more here.
Keywords: isoproterenol carbachol; ductal cells; normal conditions; cb1 ... See more keywords
Loss of Arid1a and Pten in pancreatic ductal cells induces intraductal tubulopapillary neoplasm via the YAP/TAZ pathway.
Sign Up to like & getrecommendations! Published in 2022 at "Gastroenterology"
DOI: 10.1053/j.gastro.2022.04.020
Abstract: KGROUND AND AIMS Pancreatic ductal adenocarcinoma (PDAC) arises from several types of premalignant lesions, including intraductal tubulopapillary neoplasm (ITPN); however, the molecular pathogenesis of ITPN remains unknown. METHODS We performed studies with Hnf1b-CreERT2; Ptenf/f; Arid1af/f… read more here.
Keywords: arid1a; ductal cells; itpn; taz pathway ... See more keywords
Functional differences in the role of ductal stem cells in mouse major salivary glands.
Sign Up to like & getrecommendations! Published in 2022 at "Stem cells and development"
DOI: 10.1089/scd.2022.0266
Abstract: Salivary gland (SG) stem cells are the only cell population capable of extended growth in organotypic cultures, and thus they are considered a source for cell-based therapies aimed at SG regeneration. Studies in the mouse… read more here.
Keywords: cell; expressing ductal; ductal cells; k14 expressing ... See more keywords
MUC1 and Polarity Markers INADL and SCRIB Identify Salivary Ductal Cells
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Dental Research"
DOI: 10.1177/00220345221076122
Abstract: Current treatments for xerostomia/dry mouth are palliative and largely ineffective. A permanent clinical resolution is being developed to correct hyposalivation using implanted hydrogel-encapsulated salivary human stem/progenitor cells (hS/PCs) to restore functional salivary components and increase… read more here.
Keywords: polarity markers; ductal cells; salivary ductal; markers inadl ... See more keywords
Pancreatic ductal cells may have a negative effect on human islet transplantation
Sign Up to like & getrecommendations! Published in 2019 at "PLoS ONE"
DOI: 10.1371/journal.pone.0220064
Abstract: Aim To evaluate the effect of pancreatic ductal cells on experimental human islet transplantation. Materials and methods Isolated islets were additionally purified by handpicking. Ductal cells were purified by magnetic cell sorting and then clustered… read more here.
Keywords: dps islets; islets dps; human islet; transplantation ... See more keywords
Pancreatic Duct Cells Isolated From Canines Differentiate Into Beta-Like Pancreatic Islet Cells
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Veterinary Science"
DOI: 10.3389/fvets.2021.771196
Abstract: In this study, we isolated and cultured pancreatic ductal cells from canines and revealed the possibility for using them to differentiate into functional pancreatic beta cells in vitro. Passaged pancreatic ductal cells were induced to… read more here.
Keywords: ductal cells; differentiate beta; pancreatic islet; beta like ... See more keywords