Predicted expression of genes involved in the thiopurine metabolic pathway and azathioprine discontinuation due to myelotoxicity
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DOI: 10.1111/cts.13243
Abstract: TPMT and NUDT15 variants explain less than 25% of azathioprine‐associated myelotoxicity. There are 25 additional genes in the thiopurine pathway that could also contribute to azathioprine myelotoxicity. We hypothesized that among TPMT and NUDT15 normal… read more here.
Keywords: azathioprine discontinuation; tpmt nudt15; myelotoxicity; due myelotoxicity ... See more keywords