Evaluation of domain of unknown function 1220 (DUF1220) for detection of human genome by quantitative polymerase chain reaction: Potential use in assessing the biodistribution of transplanted therapeutic human cells.
Sign Up to like & getrecommendations! Published in 2020 at "Drug metabolism and pharmacokinetics"
DOI: 10.1016/j.dmpk.2020.11.001
Abstract: The biodistribution profile of cell-based therapy products in animal models is important for evaluation of their safety and efficacy. Because of its quantitative nature and sensitivity, the quantitative polymerase chain reaction (qPCR) is a useful… read more here.
Keywords: biodistribution; duf1220; human genome; quantitative polymerase ... See more keywords
High resolution measurement of DUF1220 domain copy number from whole genome sequence data
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DOI: 10.1186/s12864-017-3976-z
Abstract: BackgroundDUF1220 protein domains found primarily in Neuroblastoma BreakPoint Family (NBPF) genes show the greatest human lineage-specific increase in copy number of any coding region in the genome. There are 302 haploid copies of DUF1220 in… read more here.
Keywords: resolution; copy number; duf1220; method ... See more keywords