Production of recombinant PvDBPII, receptor binding domain of Plasmodium vivax Duffy binding protein, and evaluation of immunogenicity to identify an adjuvant formulation for vaccine development.
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DOI: 10.1016/j.pep.2015.06.011
Abstract: Plasmodium vivax is dependent on interaction with the Duffy antigen receptor for chemokines (DARC) for invasion of human erythrocytes. The P. vivax Duffy binding protein (PvDBP) mediates interaction of P. vivax merozoites with DARC. The DARC receptor-binding… read more here.
Keywords: recombinant pvdbpii; vaccine; pvdbpii; vivax ... See more keywords
Caractérisation génétique du système Duffy à Oran
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DOI: 10.1016/j.tracli.2017.06.212
Abstract: En pathologie humaine, le systeme Duffy presente un grand interet en medecine clinique puisque ses antigenes sont impliques non seulement dans les risques transfusionnels et dans la maladie hemolytique du nouveau-ne, mais egalement dans l’invasion… read more here.
Keywords: oran; dans les; duffy; population ... See more keywords
Naturally Acquired Binding-Inhibitory Antibodies to Plasmodium vivax Duffy Binding Protein in Pregnant Women Are Associated with Higher Birth Weight in a Multicenter Study
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DOI: 10.3389/fimmu.2017.00163
Abstract: A vaccine to eliminate malaria would need a multi-stage and multi-species composition to achieve robust protection, but the lack of knowledge about antigen targets and mechanisms of protection precludes the development of fully efficacious malaria… read more here.
Keywords: pregnant women; anti; plasmodium vivax; naturally acquired ... See more keywords