Dunnione protects against experimental cisplatin-induced nephrotoxicity by modulating NQO1 and NAD+ levels
Sign Up to like & getrecommendations! Published in 2018 at "Free Radical Research"
DOI: 10.1080/10715762.2018.1475732
Abstract: Abstract Despite being an efficacious anticancer agent, the clinical utility of cisplatin is hindered by its cardinal side effects. This investigation aimed to appraise potential protective impact of dunnione, a natural naphthoquinone pigment with established… read more here.
Keywords: induced nephrotoxicity; cisplatin; nad; cisplatin induced ... See more keywords
Three new naphthoquinones from the tubers of Sinningia mauroana.
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DOI: 10.1080/14786419.2021.1969564
Abstract: Three new naphthoquinones, 5,6,7-trimethoxydunnione (1), 6,7-dimethoxy-α-dunnione (2), and 5,6,7-trimethoxydunniol (3) were isolated from the tubers of Sinningia mauroana Chautems, together with eleven known compounds: 5-hydroxy-6,7-dimethoxy-α-dunnione (4), 6-hydroxy-7-methoxy-α-dunnione (5), 7-hydroxy-6-methoxy-α-dunnione (6), cedrol (7), tectoquinone (8), plantainoside… read more here.
Keywords: tubers sinningia; antioxidant capacity; three new; sinningia mauroana ... See more keywords