DUOC‐01, a Cell Therapy Product Derived from Human Cord Blood, Accelerates Remyelination
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DOI: 10.1002/sctm.12356
Abstract: 4 We developed a cell therapy product, DUOC-01, derived from banked human umbilical cord blood, to treat demyelinating conditions in the central nervous system. Previously, we demonstrated that DUOC-01 increased myelination and decreased gliosis and… read more here.
Keywords: medicine; duoc; remyelination; cell therapy ... See more keywords
Source Cell Preparation for the Manufacture of DUOC‐01 Using a Closed System Cell‐Processing Device
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DOI: 10.1002/sctm.12566
Abstract: 17 Introduction Children treated with a cord blood transplant for demyelinating diseases suffer symptom progression until the transplant donor cells engraft in the brain. The cell product DUOC-01 was developed as an intrathecal bridging therapy… read more here.
Keywords: source cell; manufacture duoc; duoc; cell ... See more keywords
Use of Ultra‐Low Attachment Flasks Aids Manufacturing of the Macrophage‐Like Cell Therapy Product DUOC‐01 but Changes Product Phenotype
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DOI: 10.1002/sctm.12569
Abstract: 20 Introduction DUOC-01 cells are a macrophage-like cell therapy product derived from umbilical cord blood that is currently being evaluated in a phase I clinical trial for patients with congenital lysosomal storage diseases (ClinicalTrials.gov Identifier:… read more here.
Keywords: like cell; duoc; macrophage like; cell therapy ... See more keywords