Duodenal Layer Morphometry to Guide Duodenal Mucosal Resurfacing in Patients with and without Type 2 Diabetes Mellitus: Results of a Single-Center Intraluminal Imaging Pilot Study
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DOI: 10.1016/s0016-5085(17)32850-0
Abstract: Background: Endoscopic metabolic therapies, such as duodenal mucosal resurfacing (DMR) aimed at improving glycemic control in patients with Type 2 diabetes mellitus (T2DM) target the duodenal mucosa. It is unknown whether baseline differences in duodenal… read more here.
Keywords: duodenal mucosal; layer thickness; mucosal layer; mucosal ... See more keywords
Reduction of HbA1c in patients with type 2 diabetes following duodenal mucosal resurfacing: could other factors be at play?
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DOI: 10.1136/gutjnl-2020-320900
Abstract: We were interested to read the recent article by van Baar and colleagues that described an open-label phase II trial of endoscopic duodenal mucosal resurfacing (DMR) in the management of patients with type 2 diabetes… read more here.
Keywords: reduction; patients type; duodenal mucosal; type diabetes ... See more keywords
Duodenal mucosal resurfacing with a GLP-1 receptor agonist increases postprandial unconjugated bile acids in patients with insulin-dependent type 2 diabetes
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DOI: 10.1152/ajpendo.00337.2021
Abstract: INTRODUCTION Duodenal Mucosal Resurfacing (DMR) is a new endoscopic ablation technique aimed at improving glycemia and metabolic control in patients with type 2 diabetes mellitus (T2DM). DMR appears to improve insulin resistance, which is the… read more here.
Keywords: bile acid; mucosal resurfacing; duodenal mucosal; bile ... See more keywords
Duodenal mucosal mitochondrial gene expression is associated with delayed gastric emptying in diabetic gastroenteropathy
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DOI: 10.1172/jci.insight.143596
Abstract: Hindered by a limited understanding of the mechanisms responsible for diabetic gastroenteropathy (DGE), management is symptomatic. We investigated the duodenal mucosal expression of protein-coding genes and microRNAs (miRNA) in DGE and related them to clinical… read more here.
Keywords: delayed gastric; duodenal mucosal; gastric emptying; dge ... See more keywords
Duodenal Mucosal Resurfacing Elicits Improvement in Glycemic and Hepatic Parameters in Type 2 Diabetes—One-Year Multicenter Study Results
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DOI: 10.2337/db18-1137-p
Abstract: Aims: Duodenal Mucosal Resurfacing (DMR) is a novel endoscopic procedure which has been shown to improve glycemic control at 6 months in type 2 diabetes (T2D). It is thought to exert insulin-sensitizing effects. DMR entails… read more here.
Keywords: duodenal mucosal; study; self; mucosal resurfacing ... See more keywords
The Impact of Duodenal Mucosal Vulnerability in the Development of Epigastric Pain Syndrome in Functional Dyspepsia
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DOI: 10.3390/ijms232213947
Abstract: An unidentified cause of functional dyspepsia (FD) is closely associated with medication resistance. Acid suppression is a traditional and preferential method for the treatment of FD, but the efficacy of this treatment varies between epigastric… read more here.
Keywords: epigastric pain; pain syndrome; duodenal mucosal; functional dyspepsia ... See more keywords