Inhibiting translation elongation can aid genome duplication in Escherichia coli
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DOI: 10.1093/nar/gkw1254
Abstract: Abstract Conflicts between replication and transcription challenge chromosome duplication. Escherichia coli replisome movement along transcribed DNA is promoted by Rep and UvrD accessory helicases with Δrep ΔuvrD cells being inviable under rapid growth conditions. We… read more here.
Keywords: transcription; genome duplication; duplication; escherichia coli ... See more keywords