Robust, Durable Gene Activation In Vivo via mRNA-Encoded Activators.
Sign Up to like & getrecommendations! Published in 2022 at "ACS nano"
DOI: 10.1021/acsnano.1c10631
Abstract: Programmable control of gene expression via nuclease-null Cas9 fusion proteins has enabled the engineering of cellular behaviors. Here, both transcriptional and epigenetic gene activation via synthetic mRNA and lipid nanoparticle delivery was demonstrated in vivo.… read more here.
Keywords: durable gene; gene activation; activation vivo; gene ... See more keywords