Duration of action of mepivacaine and lidocaine in equine palmar digital perineural blocks in an experimental lameness model
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DOI: 10.1111/vsu.12689
Abstract: OBJECTIVE To establish and compare the onset and duration of action of 2 local anesthetics based on objective lameness and skin sensitivity assessment. STUDY DESIGN Interventional crossover experimental trial with balanced randomization. ANIMALS Eight horses.… read more here.
Keywords: duration action; mepivacaine lidocaine; mepivacaine; lameness ... See more keywords
Assessment of the Pharmacokinetics, Disposition, and Duration of Action of the Tumour-Targeting Peptide CEND-1
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DOI: 10.3390/ijms24065700
Abstract: CEND-1 (iRGD) is a bifunctional cyclic peptide that can modulate the solid tumour microenvironment, enhancing the delivery and therapeutic index of co-administered anti-cancer agents. This study explored CEND-1’s pharmacokinetic (PK) properties pre-clinically and clinically, and… read more here.
Keywords: assessment pharmacokinetics; disposition; duration action; cend ... See more keywords