Duration of antibiotic therapy in pyelonephritis: when shorter is better
Sign Up to like & getrecommendations! Published in 2020 at "Internal and Emergency Medicine"
DOI: 10.1007/s11739-020-02440-x
Abstract: Acute pyelonephritis is one of the most common serious bacterial infections, especially in young otherwise healthy women, followed by infants and older persons [1, 2]. Because of the frequency and potential seriousness of these infections,… read more here.
Keywords: medicine; treatment; pyelonephritis; duration antibiotic ... See more keywords
Evaluation of duration of antibiotic therapy across hospitals in Scotland including the impact of COVID-19 pandemic: a segmented interrupted time series analysis
Sign Up to like & getrecommendations! Published in 2023 at "Expert Review of Anti-infective Therapy"
DOI: 10.1080/14787210.2023.2181789
Abstract: ABSTRACT Background Little is known about the duration of antibiotic use in hospital settings. We evaluated the duration of hospital antibiotic therapy for four commonly prescribed antibiotics (amoxicillin, co-amoxiclav, doxycycline, and flucloxacillin) including the assessment… read more here.
Keywords: antibiotic therapy; impact; therapy; duration antibiotic ... See more keywords
Duration of Antibiotic Therapy in Necrotizing Soft Tissue Infections: Shorter is Safe.
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DOI: 10.1089/sur.2022.011
Abstract: Background: Early debridement improves outcome in necrotizing soft tissue infection (NSTI), but there is no consensus on duration of antimicrobial therapy. We recently changed practice to discontinue antibiotic agents early with a goal of 48… read more here.
Keywords: source control; duration; duration antibiotic; antibiotic agents ... See more keywords
Duration of Antibiotic Therapy and Timing of Shunt Reimplantation in Pediatric CSF Shunt Infections: A Retrospective Multicenter Case Series.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the Pediatric Infectious Diseases Society"
DOI: 10.1093/jpids/piac037
Abstract: In this retrospective multicenter series of 154 children with cerebrospinal fluid shunt infections, the median (interquartile range) duration of antibiotic therapy was 18 (14-26) days. The time to shunt replacement was 14 (10-19) days. Management… read more here.
Keywords: shunt infections; antibiotic therapy; duration antibiotic; retrospective multicenter ... See more keywords
Biomarker-guided duration of Antibiotic Treatment in Children Hospitalised with confirmed or suspected bacterial infection (BATCH): protocol for a randomised controlled trial
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DOI: 10.1136/bmjopen-2020-047490
Abstract: Introduction Procalcitonin (PCT) is a biomarker more specific for bacterial infection and responds quicker than other commonly used biomarkers such as C reactive protein, but is not routinely used in the National Health Service (NHS).… read more here.
Keywords: biomarker; infection; trial; duration antibiotic ... See more keywords
Duration of antibiotic therapy in critically ill patients: a randomized controlled trial of a clinical and C-reactive protein-based protocol versus an evidence-based best practice strategy without biomarkers
Sign Up to like & getrecommendations! Published in 2020 at "Critical Care"
DOI: 10.1186/s13054-020-02946-y
Abstract: Background The rational use of antibiotics is one of the main strategies to limit the development of bacterial resistance. We therefore sought to evaluate the effectiveness of a C-reactive protein-based protocol in reducing antibiotic treatment… read more here.
Keywords: trial; reactive protein; antibiotic therapy; critically ill ... See more keywords
Shorter Versus Longer-term Antibiotic Treatments for Community-Acquired Pneumonia in Children: A Meta-analysis.
Sign Up to like & getrecommendations! Published in 2023 at "Pediatrics"
DOI: 10.1542/peds.2022-060097
Abstract: CONTEXT The optimal duration of antibiotic treatment of children with community-acquired pneumonia (CAP) remains unclear. OBJECTIVES This study aimed to compare the efficacy and safety of shorter versus longer duration of antibiotic treatment of children… read more here.
Keywords: duration antibiotic; moderate certainty; acquired pneumonia; community acquired ... See more keywords