Automated MRI-based quantification of posterior ocular globe flattening and recovery after long-duration spaceflight
Sign Up to like & getrecommendations! Published in 2021 at "Eye"
DOI: 10.1038/s41433-021-01408-1
Abstract: Spaceflight associated neuro-ocular syndrome (SANS), a health risk related to long-duration spaceflight, is hypothesized to result from a headward fluid shift that occurs with the loss of hydrostatic pressure gradients in weightlessness. Shifts in the… read more here.
Keywords: long duration; posterior ocular; mm3 mm3; globe ... See more keywords
Limitations in predicting radiation-induced pharmaceutical instability during long-duration spaceflight
Sign Up to like & getrecommendations! Published in 2019 at "NPJ Microgravity"
DOI: 10.1038/s41526-019-0076-1
Abstract: As human spaceflight seeks to expand beyond low-Earth orbit, NASA and its international partners face numerous challenges related to ensuring the safety of their astronauts, including the need to provide a safe and effective pharmacy… read more here.
Keywords: long duration; limitations predicting; duration spaceflight; predicting radiation ... See more keywords
Reply to Ludwig et al.: A potential mechanism for intracranial cerebrospinal fluid accumulation during long-duration spaceflight
Sign Up to like & getrecommendations! Published in 2019 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.1913041116
Abstract: We thank Ludwig et al. for their interest in our work (1) and for bringing a revealing aspect of cerebrospinal fluid (CSF) dynamics to our attention (2). The flow reversal of the internal CSF circulation… read more here.
Keywords: long duration; duration spaceflight; mechanism; cerebrospinal fluid ... See more keywords
Vestibular and Cardiovascular Responses After Long-Duration Spaceflight.
Sign Up to like & getrecommendations! Published in 2020 at "Aerospace medicine and human performance"
DOI: 10.3357/amhp.5502.2020
Abstract: BACKGROUND: The vestibulo-sympathetic reflex operates during orthostatically challenging movements to initiate cardiovascular responses in advance of a baroreceptor-mediated response. The objective of this study was to determine whether there was an association between changes in… read more here.
Keywords: long duration; vestibular cardiovascular; duration spaceflight; responses long ... See more keywords
A Comprehensive Look Behind Team Composition for Long Duration Spaceflight.
Sign Up to like & getrecommendations! Published in 2023 at "Aerospace medicine and human performance"
DOI: 10.3357/amhp.6175.2023
Abstract: BACKGROUND: How to determine team composition is one of many key topics when developing humanity's next deep space exploration programs. Behavioral health and performance among spaceflight teams are key aspects impacted by team composition and… read more here.
Keywords: team composition; duration spaceflight; long duration; team ... See more keywords
Alterations in Saliva and Plasma Cytokine Concentrations During Long-Duration Spaceflight
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2021.725748
Abstract: Long-duration spaceflight is known to cause immune dysregulation in astronauts. Biomarkers of immune system function are needed to determine both the need for and effectiveness of potential immune countermeasures for astronauts. Whereas plasma cytokine concentrations… read more here.
Keywords: long duration; cytokine concentrations; duration spaceflight; plasma cytokine ... See more keywords
Brain Connectometry Changes in Space Travelers After Long-Duration Spaceflight
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Neural Circuits"
DOI: 10.3389/fncir.2022.815838
Abstract: Humans undergo extreme physiological changes when subjected to long periods of weightlessness, and as we continue to become a space-faring species, it is imperative that we fully understand the physiological changes that occur in the… read more here.
Keywords: duration spaceflight; white matter; space; long duration ... See more keywords
Neck Muscle Changes Following Long-Duration Spaceflight
Sign Up to like & getrecommendations! Published in 2019 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2019.01115
Abstract: The effects of long-duration spaceflight on crewmember neck musculature have not been adequately studied. The purpose of this study was to evaluate the changes in the neck musculature on pre-flight and post-flight magnetic resonance imaging… read more here.
Keywords: long duration; muscle; duration spaceflight; capitis ... See more keywords
The Mobile Lower Body Negative Pressure Gravity Suit for Long-Duration Spaceflight
Sign Up to like & getrecommendations! Published in 2020 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2020.00977
Abstract: Spaceflight Associated Neuro-ocular Syndrome, bone decalcification, and muscle atrophy are among the most prevalent risks associated with long-duration spaceflight. Implementing the lower body negative pressure (LBNP) method is a potential countermeasure for these risks. LBNP… read more here.
Keywords: long duration; force; duration spaceflight; gravity ... See more keywords