Dusp3 deletion in mice promotes experimental lung tumour metastasis in a macrophage dependent manner
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DOI: 10.1371/journal.pone.0185786
Abstract: Vaccinia-H1 Related (VHR) dual-specificity phosphatase, or DUSP3, plays an important role in cell cycle regulation and its expression is altered in several human cancers. In mouse model, DUSP3 deletion prevents neo-angiogenesis and b-FGF-induced microvessel outgrowth.… read more here.
Keywords: metastasis; dusp3 deletion; dusp3; mice ... See more keywords