Genome-Wide CRISPR/Cas9 Library Screening Identified that DUSP4 Deficiency Induces Lenvatinib Resistance in Hepatocellular Carcinoma
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DOI: 10.7150/ijbs.69969
Abstract: Background: Lenvatinib is in a first-line therapy for advanced hepatocellular carcinoma (HCC). However, drug resistance is one of the principal obstacles for treatment failure. The molecular mechanism of Lenvatinib resistance has not been well investigated.… read more here.
Keywords: hepatocellular carcinoma; dusp4 deficiency; genome wide; resistance ... See more keywords