MIF is essential to the establishment of house dust mite-induced airway inflammation and tissue remodeling in mice.
Sign Up to like & getrecommendations! Published in 2023 at "European journal of immunology"
DOI: 10.1002/eji.202250016
Abstract: Macrophage migration inhibitory factor (MIF) is present in high amounts in the bronchoalveolar lavage fluid (BALF) and serum of asthmatic patients contributing to the pathogenesis of experimental asthma induced by ovalbumin (OVA) in mice. Whether… read more here.
Keywords: hdm challenged; house dust; mif; mice ... See more keywords
The VEGF‐Mediated Cytoprotective Ability of MIF‐Licensed Mesenchymal Stromal Cells in House Dust Mite‐Induced Epithelial Damage
Sign Up to like & getrecommendations! Published in 2024 at "European Journal of Immunology"
DOI: 10.1002/eji.202451205
Abstract: Enhancing mesenchymal stromal cell (MSC) therapeutic efficacy through licensing with proinflammatory cytokines is now well established. We have previously shown that macrophage migration inhibitory factor (MIF)‐licensed MSCs exerted significantly enhanced therapeutic efficacy in reducing inflammation… read more here.
Keywords: house dust; mif; mesenchymal stromal; dust mite ... See more keywords
High prevalence of house dust mite sensitization in children with severe asthma living at high altitude in a tropical country
Sign Up to like & getrecommendations! Published in 2018 at "Pediatric Pulmonology"
DOI: 10.1002/ppul.24079
Abstract: Some studies, mainly in Europe, have shown a low level of sensitization to house dust mite (HDM) allergens at high altitude (HA). Differently, some others in tropical countries have shown a higher level. The aim… read more here.
Keywords: dust mite; house dust; severe asthma; children severe ... See more keywords
Storage mite concentrations are underestimated compared to house dust mite concentrations
Sign Up to like & getrecommendations! Published in 2019 at "Experimental and Applied Acarology"
DOI: 10.1007/s10493-019-00376-2
Abstract: Dwellings are increasingly well insulated to save energy and this leads to higher humidity and temperature, which improves conditions for mites. Dermatophagoides antigens are the main allergens involved and tested in atopic asthma. We developed… read more here.
Keywords: dust mite; storage mite; mite concentrations; house dust ... See more keywords
Allergic Rhinitis and House Dust Mite Sensitization Determine Persistence of Asthma in Children
Sign Up to like & getrecommendations! Published in 2022 at "Indian Journal of Pediatrics"
DOI: 10.1007/s12098-021-04052-5
Abstract: To specify clinical and immunological parameters of the mechanisms, which may lead to development of persistent asthma, or regression of the disease symptoms. Eighty children with childhood asthma, diagnosed in the past by using the… read more here.
Keywords: house dust; dust mite; allergic rhinitis; persistence ... See more keywords
Socio-environmental profile of child and adolescents sensitized by house dust mite in northeast of Brazil.
Sign Up to like & getrecommendations! Published in 2019 at "Allergologia et immunopathologia"
DOI: 10.1016/j.aller.2019.02.001
Abstract: INTRODUCTION The association regarding the atopic sensitization to mite aeroallergens and the socio-environmental features is still inconsistent. OBJECTIVES We analyzed the role played by socioeconomic and environmental factors in the prevalence of sensitization to house… read more here.
Keywords: socio environmental; ci95; house dust; dust mite ... See more keywords
Characterisation of three Novel β-1,3 glucanases from the Medically Important House Dust Mite Dermatophagoides pteronyssinus (airmid).
Sign Up to like & getrecommendations! Published in 2019 at "Insect biochemistry and molecular biology"
DOI: 10.1016/j.ibmb.2019.103242
Abstract: The European house dust mite, Dermatophagoides pteronyssinus is a major source of airborne allergens worldwide and is found in half of European homes. Interactions between microbes and house dust mites (HDM) are considered important factors… read more here.
Keywords: pteronyssinus airmid; dust mite; house dust;
Multi-Method Molecular Characterisation of Human Dust-Mite-associated Allergic Asthma
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-45257-1
Abstract: Asthma is a chronic inflammatory disorder of the airways. Disease presentation varies greatly in terms of cause, development, severity, and response to medication, and thus the condition has been subdivided into a number of asthma… read more here.
Keywords: asthma; control; group; dust mite ... See more keywords
Der p 1-based immunotoxin as potential tool for the treatment of dust mite respiratory allergy
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-69166-w
Abstract: Immunotoxins appear as promising therapeutic molecules, alternative to allergen-specific-immunotherapy. In this work, we achieved the development of a protein chimera able to promote specific cell death on effector cells involved in the allergic reaction. Der… read more here.
Keywords: dust mite; immunotoxin potential; based immunotoxin; der ... See more keywords
Extent of allergic inflammation depends on intermittent versus continuous sensitization to house dust mite
Sign Up to like & getrecommendations! Published in 2017 at "Inhalation Toxicology"
DOI: 10.1080/08958378.2017.1311389
Abstract: Abstract Objective: House dust mite (HDM) exposure is used to model experimental asthma in mice. However, a direct comparison of inflammatory responses following continuous versus intermittent HDM exposure has not been reported. Therefore, we investigated… read more here.
Keywords: house dust; dust mite; inflammation; hdm ... See more keywords
Computational investigation of dust mite allergens in a realistic human nasal cavity
Sign Up to like & getrecommendations! Published in 2019 at "Inhalation Toxicology"
DOI: 10.1080/08958378.2019.1647315
Abstract: Abstract Aim: Inhaled allergens from house dust mite (HDM) are a major source of allergic disease such as allergic rhinitis and asthma. It has been a challenge to properly evaluate health risks caused by HDM… read more here.
Keywords: human nasal; mite allergens; dust mite; nasal cavity ... See more keywords