Articles with "dvl1" as a keyword



Downregulated miR-1247-5p associates with poor prognosis and facilitates tumor cell growth via DVL1/Wnt/β-catenin signaling in breast cancer.

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Published in 2018 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2018.09.103

Abstract: The abnormal expression of microRNAs is a key hallmark of breast cancer. Nevertheless, the biological roles of miR-1247-5p in breast cancer remain unknown. In this study, we revealed that miR-1247-5p expression was markedly decreased in… read more here.

Keywords: poor prognosis; breast cancer; mir 1247; dvl1 ... See more keywords

Dishevelled-1 regulates global transcriptomic changes and associates with ETS1 transcription factor

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Published in 2025 at "Nature Communications"

DOI: 10.1038/s41467-025-61551-1

Abstract: Dishevelled (DVL) is a crucial component of the Wnt-signaling pathway and is vital for multiple physiological processes. Previously thought to have a classically cytoplasmic role, the discovery of DVL nuclear translocation reframed how it is… read more here.

Keywords: transcription factor; nuclear dvl1; ets1 transcription; dvl1 ... See more keywords

Evaluation of LRP6, SFRP3, and DVL1 Protein Concentrations in Serum of Patients with Gastroenteropancreatic or Bronchopulmonary Neuroendocrine Tumors

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Published in 2024 at "Cancers"

DOI: 10.3390/cancers17010047

Abstract: Simple Summary This retrospective study investigated the serum levels of LRP6, SFRP3, and DVL1 in patients with neuroendocrine tumors (NETs) and a control group using the ELISA method. The results showed significantly elevated SFRP3 levels… read more here.

Keywords: lrp6 sfrp3; evaluation lrp6; sfrp3 dvl1; neuroendocrine tumors ... See more keywords

Decoding the Role of DVL1 in Intracranial Meningioma

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Published in 2021 at "International Journal of Molecular Sciences"

DOI: 10.3390/ijms222111996

Abstract: In the search for molecular candidates for targeted meningioma therapies, increasing attention has been paid to the role of signaling pathways in the development and progression of intracranial meningiomas. Although it is well known that… read more here.

Keywords: decoding role; meningioma; dvl1; role dvl1 ... See more keywords