Dishevelled-3 phosphorylation is governed by HIPK2/PP1Cα/ITCH axis and the non-phosphorylated form promotes cancer stemness via LGR5 in hepatocellular carcinoma
Sign Up to like & getrecommendations! Published in 2017 at "Oncotarget"
DOI: 10.18632/oncotarget.17049
Abstract: Dishevelled-3 (Dvl3) is regarded as a binding hub with many different interacting partners. However, its regulation and mechanism on cancer stemness remain to be explored. In this study, we showed that Dvl3 was significantly overexpressed… read more here.
Keywords: dvl3; itch; phosphorylation; cancer stemness ... See more keywords
Investigating Radiotherapy Response in a Novel Syngeneic Model of Prostate Cancer
Sign Up to like & getrecommendations! Published in 2020 at "Cancers"
DOI: 10.3390/cancers12102804
Abstract: Simple Summary Pre-clinical models are required to develop new therapeutics to improve patient care. In the prostate cancer field, significant progress has been made in the development of in vivo models but with a predominant… read more here.
Keywords: dvl3; model; pca; prostate cancer ... See more keywords
Aberrant expression of SFRP1, SFRP3, DVL2 and DVL3 Wnt signaling pathway components in diffuse gastric carcinoma
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DOI: 10.3892/ol.2021.13083
Abstract: Diffuse gastric carcinoma (DGC) is characterized by poorly cohesive cells, highly invasive growth patterns, poor prognosis and resistance to the majority of available systemic therapeutic strategies. It has been previously reported that the Wnt/β-catenin signaling… read more here.
Keywords: sfrp3; dvl3; dgc; dvl2 ... See more keywords