DW14383 is an irreversible pan-FGFR inhibitor that suppresses FGFR-dependent tumor growth in vitro and in vivo.
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DOI: 10.1038/s41401-020-00567-3
Abstract: Fibroblast growth factor receptor (FGFR) is a promising anticancer target. Currently, most FGFR inhibitors lack sufficient selectivity and have nonnegligible activity against kinase insert domain receptor (KDR), limiting their feasibility due to the serious side… read more here.
Keywords: dw14383; fgfr; fgfr inhibitor; fgfr1 ... See more keywords