Unknown‐onset strokes with anterior circulation occlusion treated by thrombectomy after DWI‐FLAIR mismatch selection
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DOI: 10.1111/ene.13580
Abstract: The DAWN trial recently showed compelling evidence in treating late window and wake‐up stroke patients with thrombectomy using a clinical‐imaging mismatch. The aim was to evaluate the results of thrombectomy for unknown‐onset strokes (UOS) treated… read more here.
Keywords: flair mismatch; dwi flair; onset strokes; unknown onset ... See more keywords
Abstract WP86: MRI-Guided Mismatch Imaging to Identify Patients for Thrombolysis in the Unknown Time Window: Insights From the WAKE-UP Trial
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DOI: 10.1161/str.51.suppl_1.wp86
Abstract: Background: Two imaging paradigms, the diffusion-weighted imaging (DWI) - fluid attenuated inversion recovery (FLAIR) and perfusion-weighted imaging (PWI) - DWI mismatch, used in the Efficacy and Safety of MRI-Based Thrombolysis in Wake-Up Stroke (WAKE-UP) and… read more here.
Keywords: pwi dwi; dwi mismatch; dwi flair; mismatch ... See more keywords
Automated DWI analysis can identify patients within the thrombolysis time window of 4.5 hours
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DOI: 10.1212/wnl.0000000000005413
Abstract: Objective To develop an automated model based on diffusion-weighted imaging (DWI) to detect patients within 4.5 hours after stroke onset and compare this method to the visual DWI-FLAIR (fluid-attenuated inversion recovery) mismatch. Methods We performed… read more here.
Keywords: time window; dwi flair; patients within; flair ... See more keywords
Use of DWI-FLAIR Mismatch to Estimate the Onset Time in Wake-Up Strokes
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DOI: 10.2147/ndt.s351943
Abstract: Purpose To compare the MRI characteristics of patients with wake-up ischemic stroke (WUS) and with ischemic stroke with known onset time (clear-onset-time stroke, COS) to clarify the role of diffusion-weighted imaging–fluid-attenuated inversion recovery (DWI-FLAIR) mismatch… read more here.
Keywords: flair mismatch; flair; dwi flair; onset time ... See more keywords
CDC42 Might Be a Molecular Signature of DWI-FLAIR Mismatch in a Nonhuman Primate Stroke Model
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DOI: 10.3390/brainsci13020287
Abstract: No definitive blood markers of DWI-FLAIR mismatch, a pivotal indicator of salvageable ischemic penumbra brain tissue, are known. We previously reported that CDC42 and RHOA are associated with the ischemic penumbra. Here, we investigated whether… read more here.
Keywords: flair mismatch; dwi flair; flair; cdc42 ... See more keywords