Sign Up to like & get
recommendations!
1
Published in 2022 at "Biochemistry"
DOI: 10.1021/acs.biochem.2c00274
Abstract: The bacterial enzyme 1-deoxy-d-xylulose 5-phosphate synthase (DXPS) catalyzes the formation of DXP from pyruvate and d-glyceraldehyde 3-phosphate (d-GAP) in a thiamin diphosphate (ThDP)-dependent manner. In addition to its role in isoprenoid biosynthesis, DXP is required…
read more here.
Keywords:
phosphate;
synthase;
dxps;
donor ... See more keywords
Sign Up to like & get
recommendations!
1
Published in 2023 at "Antibiotics"
DOI: 10.3390/antibiotics12040692
Abstract: Pathogenic bacteria possess a remarkable ability to adapt to fluctuating host environments and cause infection. Disturbing bacterial central metabolism through inhibition of 1-deoxy-d-xylulose 5-phosphate synthase (DXPS) has the potential to hinder bacterial adaptation, representing a…
read more here.
Keywords:
function;
adaptation;
metabolic adaptation;
antibacterial strategies ... See more keywords