CMYA5 establishes cardiac dyad architecture and positioning.
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DOI: 10.1038/s41467-022-29902-4
Abstract: Cardiac excitation-contraction coupling requires dyads, the nanoscopic microdomains formed adjacent to Z-lines by apposition of transverse tubules and junctional sarcoplasmic reticulum. Disruption of dyad architecture and function are common features of diseased cardiomyocytes. However, little… read more here.
Keywords: sarcoplasmic reticulum; architecture; junctional sarcoplasmic; dyad architecture ... See more keywords