Minimizing control group allocation in randomized trials using dynamic borrowing of external control data – An application to second line therapy for non-small cell lung cancer
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DOI: 10.1016/j.conctc.2019.100446
Abstract: Background Enrollment of participants to control arms in clinical trials can be challenging. This is particularly an issue in oncology trials where the standard-of-care is shifting rapidly and several promising experimental treatments are undergoing phase… read more here.
Keywords: control group; control; dynamic borrowing; clinical trials ... See more keywords