Dynamic cancer drivers: a causal approach for cancer driver discovery based on bio-pathological trajectories.
Sign Up to like & getrecommendations! Published in 2022 at "Briefings in functional genomics"
DOI: 10.1093/bfgp/elac030
Abstract: The traditional way for discovering genes which drive cancer (namely cancer drivers) neglects the dynamic information of cancer development, even though it is well known that cancer progresses dynamically. To enhance cancer driver discovery, we… read more here.
Keywords: driver; cancer drivers; cancer driver; dynamic cancer ... See more keywords
Dynamic Cancer Cell Heterogeneity: Diagnostic and Therapeutic Implications
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DOI: 10.3390/cancers14020280
Abstract: Simple Summary Cancer heterogeneity, which occurs in most cancer patients, has been known and studied by experienced pathologists since the early 19th century. Intratumoral heterogeneity between cancer cells can arise from complex genetic, epigenetic, and… read more here.
Keywords: cell; heterogeneity; therapeutic implications; diagnostic therapeutic ... See more keywords