LAUSR

Dynamic Continuum of Nanoscale Peptide Assemblies Facilitates Endocytosis and Endosomal Escape.

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0 Published in 2021 at "Nano letters"

DOI: 10.1021/acs.nanolett.1c01029

Abstract: Alkaline phosphatase (ALP) enables intracellular targeting by peptide assemblies, but how the ALP substrates enter cells remains elusive. Here we show that nanoscale phosphopeptide assemblies cluster ALP to enable caveolae-mediated endocytosis (CME) and endosomal escape.… read more here.

Keywords: peptide assemblies; continuum nanoscale; escape; endocytosis ... See more keywords