Structural and Dynamic Differences between Calreticulin Mutants Associated with Essential Thrombocythemia
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DOI: 10.3390/biom13030509
Abstract: Essential thrombocythemia (ET) is a blood cancer. ET is characterized by an overproduction of platelets that can lead to thrombosis formation. Platelet overproduction occurs in megakaryocytes through a signaling pathway that could involve JAK2, MPL,… read more here.
Keywords: essential thrombocythemia; differences calreticulin; dynamic differences; calreticulin mutants ... See more keywords