Dynamic Generation of G-Quadruplex DNA Ligands by Target-Guided Combinatorial Chemistry on a Magnetic Nanoplatform.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of medicinal chemistry"
DOI: 10.1021/acs.jmedchem.8b01459
Abstract: Dynamic combinatorial chemistry (DCC) has emerged as a promising strategy for template-driven selection of high-affinity ligands for biological targets from equilibrating combinatorial libraries. However, only a few examples using disulfide-exchange-based DCC are reported for nucleic… read more here.
Keywords: generation quadruplex; dna; combinatorial chemistry; quadruplex dna ... See more keywords
A Front Advancing Adaptive Triangular Mesh Dynamic Generation Algorithm and Its Application in 3D Geological Modeling
Sign Up to like & getrecommendations! Published in 2023 at "Sustainability"
DOI: 10.3390/su15097214
Abstract: The traditional advancing front technique algorithm encounters many problems due to the complex geometric characteristics of the front edge shape. These problems include poor quality, a slow algorithm, low robustness, and the inability of the… read more here.
Keywords: front; algorithm; dynamic generation; mesh dynamic ... See more keywords