Composite Dynamic Hydrogels Constructed on Boronic Ester Cross-Links with NIR-Enhanced Diffusivity.
Sign Up to like & getrecommendations! Published in 2022 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.1c01359
Abstract: Dynamic hydrogels with thermosensitive cross-links are highly promising platforms for "on-demand" drug delivery systems. However, there is a problem with triggering a response in their whole volume, which reduces their efficiency. To achieve better thermoresponsiveness,… read more here.
Keywords: cross links; dynamic hydrogels; boronic ester; diffusivity ... See more keywords
Microscopic local stiffening in a supramolecular hydrogel network expedites stem cell mechanosensing in 3D and bone regeneration.
Sign Up to like & getrecommendations! Published in 2021 at "Materials horizons"
DOI: 10.1039/d1mh00244a
Abstract: Dynamic hydrogels cross-linked by weak and reversible physical interactions enhance the 3-dimensional (3D) spreading and mechanosensing abilities of encapsulated cells in a matrix. However, the highly dynamic nature of these physical cross-links also results in… read more here.
Keywords: hydrogel network; stem; cell; dynamic hydrogels ... See more keywords
Synthetic, multi-dynamic hydrogels by uniting stress-stiffening and supramolecular polymers.
Sign Up to like & getrecommendations! Published in 2024 at "Science advances"
DOI: 10.1126/sciadv.adr3209
Abstract: Nature uses discrete molecular building blocks to form polymers that assemble into multicomponent, multi-dynamic networks, inside (cytoskeleton) and outside (extracellular matrix) the cell. Both the intra-fibrous molecular dynamics and interactions between fibers dictate (non)linear mechanics,… read more here.
Keywords: stress stiffening; dynamic hydrogels; supramolecular polymers; multi dynamic ... See more keywords
Dynamic Hydrogels: Adaptive Biomaterials for Engineering Tumor Microenvironment and Cancer Treatment
Sign Up to like & getrecommendations! Published in 2025 at "International Journal of Molecular Sciences"
DOI: 10.3390/ijms26199502
Abstract: Dynamic hydrogels are revolutionizing tumor microenvironment (TME) engineering through their stimuli-responsive adaptability, mechanical tunability, and capacity for multifunctional integration. In addition, they are excellent biomaterials for cancer treatments, including their biomimetic properties and controlled cargo… read more here.
Keywords: dynamic hydrogels; tumor microenvironment; microenvironment cancer;