Engineering Biomolecular Switches for Dynamic Metabolic Control.
Sign Up to like & getrecommendations! Published in 2018 at "Advances in biochemical engineering/biotechnology"
DOI: 10.1007/10_2016_9
Abstract: Living organisms have been exploited as production hosts for a large variety of compounds. To improve the efficiency of bioproduction, metabolic pathways in an organism are usually manipulated by various genetic modifications. However, bottlenecks during… read more here.
Keywords: engineering; switches dynamic; engineering biomolecular; control ... See more keywords
Application of a dynamic metabolic flux algorithm during a temperature-induced lag phase
Sign Up to like & getrecommendations! Published in 2017 at "Food and Bioproducts Processing"
DOI: 10.1016/j.fbp.2016.10.003
Abstract: Abstract In predictive microbiology, the (induced) lag-phase is a phenomenon of specific interest, as it has a large impact on the assessment of safety and quality of food products. This lag phase has been studied… read more here.
Keywords: phase; lag phase; temperature; microbiology ... See more keywords
Dynamic metabolic engineering of Escherichia coli improves fermentation for the production of pyruvate and its derivatives.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of bioscience and bioengineering"
DOI: 10.1016/j.jbiosc.2021.09.015
Abstract: Pyruvate is a key intermediate that is involved in various synthetic metabolic pathways for microbial chemical and fuel production. It is widely used in the food, chemical, and pharmaceutical industries. However, the microbial production of… read more here.
Keywords: pyruvate derivatives; production; pyruvate; metabolic engineering ... See more keywords
Design of Synthetic Quorum Sensing Achieving Induction Timing-Independent Signal Stabilization for Dynamic Metabolic Engineering of E. coli.
Sign Up to like & getrecommendations! Published in 2021 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.1c00008
Abstract: Dynamic metabolic engineering that harnesses synthetic biological tools is a next-generation strategy for microbial chemical and fuel production. We previously reported a synthetic quorum sensing system combined with a metabolic toggle switch (QS-MTS) in E. coli.… read more here.
Keywords: synthetic quorum; metabolic engineering; induction timing; quorum sensing ... See more keywords
Value of dynamic metabolic curves and artificial neural network prediction models based on 18F-FDG PET/CT multiphase imaging in differentiating nonspecific solitary pulmonary lesions: a pilot study
Sign Up to like & getrecommendations! Published in 2022 at "Nuclear Medicine Communications"
DOI: 10.1097/mnm.0000000000001627
Abstract: Objective To investigate the value of dynamic metabolic curves and artificial neural network prediction models based on 18F-FDG PET multiphase imaging in differentiating nonspecific solitary pulmonary lesions. Methods This study enrolled 71 patients with solitary… read more here.
Keywords: metabolic curves; neural network; solitary pulmonary; pulmonary lesions ... See more keywords
Dynamic Metabolic Changes During Prolonged Ex Situ Heart Perfusion Are Associated With Myocardial Functional Decline
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2022.859506
Abstract: Ex situ heart perfusion (ESHP) was developed to preserve and evaluate donated hearts in a perfused beating state. However, myocardial function declines during ESHP, which limits the duration of perfusion and the potential to expand… read more here.
Keywords: spme; perfusion; heart perfusion; heart ... See more keywords