Hierarchical dynamic regulation of Saccharomyces cerevisiae for enhanced lutein biosynthesis
Sign Up to like & getrecommendations! Published in 2022 at "Biotechnology and Bioengineering"
DOI: 10.1002/bit.28286
Abstract: Lutein, as a carotenoid with strong antioxidant capacity and an important component of macular pigment in the retina, has wide applications in pharmaceutical, food, feed, and cosmetics industries. Besides extraction from plant and algae, microbial… read more here.
Keywords: hierarchical dynamic; lutein biosynthesis; dynamic regulation; production ... See more keywords
Dynamic regulation of Zn(II) sequestration by calgranulin C
Sign Up to like & getrecommendations! Published in 2022 at "Protein Science"
DOI: 10.1002/pro.4403
Abstract: Calgranulin C performs antimicrobial activity in the human immune response by sequestering Zn(II). This biological function is afforded with the aid of two structurally distinct Ca(II)‐binding EF hand motifs, wherein one of which bears an… read more here.
Keywords: sequestration calgranulin; state; calgranulin; dynamic regulation ... See more keywords
Dynamic Regulation of SARS-Cov-2 Binding and Cell Entry Mechanisms in Remodeled Human Ventricular Myocardium
Sign Up to like & getrecommendations! Published in 2020 at "JACC: Basic to Translational Science"
DOI: 10.1016/j.jacbts.2020.06.007
Abstract: SUMMARY Using serial analysis of myocardial gene expression employing endomyocardial biopsy starting material in a dilated cardiomyopathy cohort, we show that the SARS-CoV-2 cardiac myocyte receptor ACE2 is upregulated with remodeling and with reverse remodeling… read more here.
Keywords: cov binding; regulation sars; entry; sars cov ... See more keywords
Balancing Pyruvate Node Based on a Dual-Layered Dynamic Regulation System to Improve the Biosynthesis of Caffeic Acid in Candida glycerinogenes.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of agricultural and food chemistry"
DOI: 10.1021/acs.jafc.3c01722
Abstract: Caffeic acid is a phenolic acid compound widely applied in the food and pharmaceutical fields. Currently, one of the reasons for the low yield of caffeic acid biosynthesis is that the carbon flow enters mainly… read more here.
Keywords: system; dual layered; layered dynamic; dynamic regulation ... See more keywords
Engineering 1-Alkene Biosynthesis and Secretion by Dynamic Regulation in Yeast.
Sign Up to like & getrecommendations! Published in 2018 at "ACS synthetic biology"
DOI: 10.1021/acssynbio.7b00338
Abstract: Microbial production of fatty acid-derived hydrocarbons offers a great opportunity to sustainably supply biofuels and oleochemicals. One challenge is to achieve a high production rate. Besides, low efficiency in secretion will cause high separation costs,… read more here.
Keywords: engineering; secretion; production; yeast ... See more keywords
Intracellular biosensor-based dynamic regulation to manipulate gene expression at the spatiotemporal level.
Sign Up to like & getrecommendations! Published in 2022 at "Critical reviews in biotechnology"
DOI: 10.1080/07388551.2022.2040415
Abstract: The use of intracellular, biosensor-based dynamic regulation strategies to regulate and improve the production of useful compounds have progressed significantly over previous decades. By employing such an approach, it is possible to simultaneously realize high… read more here.
Keywords: biosensor based; intracellular biosensor; regulation; level ... See more keywords
The chromatin signatures of enhancers and their dynamic regulation
Sign Up to like & getrecommendations! Published in 2023 at "Nucleus"
DOI: 10.1080/19491034.2022.2160551
Abstract: ABSTRACT Enhancers are cis-regulatory elements that can stimulate gene expression from distance, and drive precise spatiotemporal gene expression profiles during development. Functional enhancers display specific features including an open chromatin conformation, Histone H3 lysine 27… read more here.
Keywords: dynamic regulation; gene expression; chromatin signatures; chromatin ... See more keywords
Dynamic regulation of anthocyanin biosynthesis at different light intensities by the BT2-TCP46-MYB1 module in apple
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Experimental Botany"
DOI: 10.1093/jxb/eraa056
Abstract: An apple TCP transcription factor, MdTCP46, is induced by high light intensity and interacts with MdMYB1 to promote expression of anthocyanin biosynthesis genes. read more here.
Keywords: regulation anthocyanin; anthocyanin biosynthesis; dynamic regulation; apple ... See more keywords
Asymptotic Tracking and Dynamic Regulation of MIMO Nonaffine Nonlinear System With Actuator Saturation via Multidimensional Taylor Network Controller
Sign Up to like & getrecommendations! Published in 2022 at "IEEE Transactions on Systems, Man, and Cybernetics: Systems"
DOI: 10.1109/tsmc.2021.3106314
Abstract: Control input acting on the system in the form of nonlinear implicit tends to exert great impacts on the dynamic behavior of the multiple-input–multiple-output (MIMO) nonaffine nonlinear system with actuator saturation, posing a great challenge… read more here.
Keywords: system; nonaffine nonlinear; controller; dynamic regulation ... See more keywords
Transcription factor-based biosensors for screening and dynamic regulation
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Bioengineering and Biotechnology"
DOI: 10.3389/fbioe.2023.1118702
Abstract: Advances in synthetic biology and genetic engineering are bringing into the spotlight a wide range of bio-based applications that demand better sensing and control of biological behaviours. Transcription factor (TF)-based biosensors are promising tools that… read more here.
Keywords: factor based; based biosensors; transcription; dynamic regulation ... See more keywords
Spatiotemporal Dynamic Regulation of Organelles During Meiotic Development, Insights From Fungi
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cell and Developmental Biology"
DOI: 10.3389/fcell.2022.886710
Abstract: Eukaryotic cell development involves precise regulation of organelle activity and dynamics, which adapt the cell architecture and metabolism to the changing developmental requirements. Research in various fungal model organisms has disclosed that meiotic development involves… read more here.
Keywords: spatiotemporal dynamic; meiotic development; development; dynamic regulation ... See more keywords