Dynamic Transcriptional and Epigenetic Changes Drive Cellular Plasticity in the Liver
Sign Up to like & getrecommendations! Published in 2021 at "Hepatology"
DOI: 10.1002/hep.31704
Abstract: Following liver injury, a fraction of hepatocytes adopt features of biliary epithelial cells (BECs) in a process known as biliary reprogramming. The aim of this study was to elucidate the molecular events accompanying this dramatic… read more here.
Keywords: dynamic transcriptional; cellular plasticity; changes drive; epigenetic changes ... See more keywords
Complex and dynamic transcriptional changes allow the helminth Fasciola gigantica to adjust to its intermediate snail and definitive mammalian hosts
Sign Up to like & getrecommendations! Published in 2019 at "BMC Genomics"
DOI: 10.1186/s12864-019-6103-5
Abstract: BackgroundThe tropical liver fluke, Fasciola gigantica causes fasciolosis, an important disease of humans and livestock. We characterized dynamic transcriptional changes associated with the development of the parasite in its two hosts, the snail intermediate host… read more here.
Keywords: fasciola; dynamic transcriptional; fasciola gigantica; snail ... See more keywords