On the Conformational Dynamics of β-Amyloid Forming Peptides: A Computational Perspective
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DOI: 10.3389/fbioe.2020.00532
Abstract: Understanding the conformational dynamics of proteins and peptides involved in important functions is still a difficult task in computational structural biology. Because such conformational transitions in β-amyloid (Aβ) forming peptides play a crucial role in… read more here.
Keywords: forming peptides; conformational dynamics; peptides computational; dynamics amyloid ... See more keywords
Effects of Acute Sepsis on Cellular Dynamics and Amyloid Formation in a Mouse Model of Alzheimer’s Disease
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DOI: 10.3390/cimb44090262
Abstract: Our objective was to investigate how sepsis influences cellular dynamics and amyloid formation before and after plaque formation. As such, APP-mice were subjected to a polymicrobial abdominal infection resulting in sepsis at 2 (EarlySepsis) and… read more here.
Keywords: sepsis; amyloid formation; cellular dynamics; formation ... See more keywords