Investigation of Atrial Natriuretic Peptide as A Competitive Inhibitory Candidate Against Wnt/β-Catenin Signalling: A Molecular Dynamics Approach
Sign Up to like & getrecommendations! Published in 2020 at "International Journal of Peptide Research and Therapeutics"
DOI: 10.1007/s10989-020-10085-9
Abstract: Wnt/β-catenin signaling, a highly evolutionary conserved pathway, is abnormally regulated in many human cancers. This pathway is one of the proposed mechanisms of atrial natriuretic peptide (ANP) anti-cancer effect. ANP which at first reported as… read more here.
Keywords: atrial natriuretic; wnt; molecular dynamics; dynamics approach ... See more keywords
A molecular dynamics approach to explore the structural characterization of cataract causing mutation R58H on human γD crystallin
Sign Up to like & getrecommendations! Published in 2018 at "Molecular and Cellular Biochemistry"
DOI: 10.1007/s11010-018-3342-8
Abstract: The crystallins are a family of monomeric proteins present in the mammalian lens and mutations in these proteins cause various forms of cataracts. The aim of our current study is to emphasize the structural characterization… read more here.
Keywords: r58h; molecular dynamics; dynamics approach; crystallin ... See more keywords
A Langevin dynamics approach for multi-layer mass transfer problems
Sign Up to like & getrecommendations! Published in 2020 at "Computers in biology and medicine"
DOI: 10.1016/j.compbiomed.2020.103932
Abstract: We use Langevin dynamics simulations to study the mass diffusion problem across two adjacent porous layers of different transport properties. At the interface between the layers, we impose the Kedem-Katchalsky (KK) interfacial boundary condition that… read more here.
Keywords: layer; multi layer; langevin dynamics; dynamics approach ... See more keywords
Assessing the pollution convergence across Chinese cities by considering ecological indicators: A continuous distribution dynamics approach
Sign Up to like & getrecommendations! Published in 2021 at "Ecological Indicators"
DOI: 10.1016/j.ecolind.2021.107552
Abstract: Abstract We employ a nonparametric distribution dynamics approach to examine the long-run trend of particulate matter (PM2.5) air pollution in China. Analysis of the data from 288 Chinese prefectural and above (PAA) level cities over… read more here.
Keywords: distribution dynamics; ecological indicators; convergence; dynamics approach ... See more keywords
Heterogeneous agent models in financial markets: A nonlinear dynamics approach
Sign Up to like & getrecommendations! Published in 2019 at "International Review of Financial Analysis"
DOI: 10.1016/j.irfa.2018.11.016
Abstract: Studies on financial markets have accumulated consistent evidences of stylized facts and anomalies, which can be characterized by stochastic switching among different co-existing market states but yet difficult to reconcile with traditionally rational expectation theory.… read more here.
Keywords: facts anomalies; financial markets; stylized facts; dynamics approach ... See more keywords
The conceptualization of societal impacts of landfill mining – A system dynamics approach
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Cleaner Production"
DOI: 10.1016/j.jclepro.2021.126351
Abstract: Abstract Landfill mining (LFM) refers to the excavation and processing of formerly buried waste streams. It offers significant environmental and societal benefits through the mitigation of greenhouse gas emissions or the reduction of long-term waste… read more here.
Keywords: system dynamics; dynamics approach; landfill mining; societal impacts ... See more keywords
Discrete Molecular Dynamics Approach to the Study of Disordered and Aggregating Proteins.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of chemical theory and computation"
DOI: 10.1021/acs.jctc.6b01153
Abstract: We present a refinement of the Coarse Grained PACSAB force field for Discrete Molecular Dynamics (DMD) simulations of proteins in aqueous conditions. As the original version, the refined method provides good representation of the structure… read more here.
Keywords: disordered aggregating; molecular dynamics; dynamics approach; study disordered ... See more keywords
Expediting dynamics approach to understand the influence of 14-3-3ζ causing metastatic cancer through the interaction of YAP1 and β-TRCP.
Sign Up to like & getrecommendations! Published in 2017 at "Molecular bioSystems"
DOI: 10.1039/c7mb00271h
Abstract: The 14-3-3ζ protein acts as a molecular switch in regulating the TGF-β pathway, which alters from a tumor suppressor in the early stage of breast cancer to a promoter of metastasis in the late stage.… read more here.
Keywords: expediting dynamics; interaction yap1; yap1 trcp; dynamics approach ... See more keywords
New evidence on the convergence and regional clusters in China: a weighted continuous distribution dynamics approach
Sign Up to like & getrecommendations! Published in 2020 at "Applied Economics"
DOI: 10.1080/00036846.2020.1820443
Abstract: ABSTRACT This paper examines income convergence by using a continuous distribution dynamics approach which takes both population and economic size into consideration. The study is based on a panel dataset of 31 Chinese provinces from… read more here.
Keywords: distribution dynamics; continuous distribution; dynamics approach; reform period ... See more keywords
Molecular docking and dynamics approach to in silico drug repurposing for inflammatory bowels disease by targeting TNF alpha
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Biomolecular Structure and Dynamics"
DOI: 10.1080/07391102.2022.2050948
Abstract: Abstract Inflammatory bowel disease is a chronic disorder of the large intestine with the prevalence of approximately 400 cases in 100000, and it is rising day by day. However, several drugs like sulfasalazine (composed of… read more here.
Keywords: molecular docking; approach silico; tnf; docking dynamics ... See more keywords
A discrete dynamics approach to sparse calculation and applied in ontology science
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Difference Equations and Applications"
DOI: 10.1080/10236198.2018.1551383
Abstract: ABSTRACT In the era of big data, with the increase of data processing information and the increase of data complexity, higher requirements are put on the tools and algorithms of data processing. As a tool… read more here.
Keywords: ontology; discrete dynamics; applied ontology; dynamics approach ... See more keywords