CYRI proteins: controllers of actin dynamics in the cellular ‘eat vs walk’ decision
Sign Up to like & getrecommendations! Published in 2023 at "Biochemical Society Transactions"
DOI: 10.1042/bst20221354
Abstract: Cells use actin-based protrusions not only to migrate, but also to sample their environment and take up liquids and particles, including nutrients, antigens and pathogens. Lamellipodia are sheet-like actin-based protrusions involved in sensing the substratum… read more here.
Keywords: actin dynamics; controllers actin; proteins controllers; dynamics cellular ... See more keywords
Emergent dynamics of cellular decision making in multi-node mutually repressive regulatory networks
Sign Up to like & getrecommendations! Published in 2025 at "Journal of the Royal Society Interface"
DOI: 10.1098/rsif.2025.0190
Abstract: Stem cell differentiation during development is governed by the dynamics of the underlying gene regulatory networks (GRNs). Mutually inhibiting nodes/collection of nodes encompass the GRNs that govern differentiation to two distinct fates. But the properties… read more here.
Keywords: differentiation; decision making; cellular decision; emergent dynamics ... See more keywords
Multiscale modelling of bioprocess dynamics and cellular growth
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DOI: 10.1186/s12934-024-02581-0
Abstract: Fermentation processes are essential for the production of small molecules, heterologous proteins and other commercially important products. Traditional bioprocess optimisation relies on phenomenological models that focus on macroscale variables like biomass growth and protein yield.… read more here.
Keywords: modelling bioprocess; cellular growth; dynamics cellular; multiscale modelling ... See more keywords
Agent-Based Modeling of Mitochondria Links Sub-Cellular Dynamics to Cellular Homeostasis and Heterogeneity
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DOI: 10.1371/journal.pone.0168198
Abstract: Mitochondria are semi-autonomous organelles that supply energy for cellular biochemistry through oxidative phosphorylation. Within a cell, hundreds of mobile mitochondria undergo fusion and fission events to form a dynamic network. These morphological and mobility dynamics… read more here.
Keywords: homeostasis; heterogeneity; dynamics cellular; based modeling ... See more keywords