The “Self-Stirred” Genome: Bulk and Surface Dynamics of the Chromatin Globule
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DOI: 10.1016/j.bpj.2016.11.999
Abstract: Chromatin structure and dynamics control all aspects of DNA biology yet are poorly understood. In interphase, time between two cell divisions, chromatin fills the cell nucleus in its minimally condensed polymeric state. Chromatin serves as… read more here.
Keywords: chromatin globule; chromatin; chromatin dynamics; surface dynamics ... See more keywords
Recent Advances in Investigating Functional Dynamics of Chromatin
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DOI: 10.3389/fgene.2022.870640
Abstract: Dynamics spanning the picosecond-minute time domain and the atomic-subcellular spatial window have been observed for chromatin in vitro and in vivo. The condensed organization of chromatin in eukaryotic cells prevents regulatory factors from accessing genomic… read more here.
Keywords: dynamics chromatin; advances investigating; functional dynamics; investigating functional ... See more keywords
A Liquid State Perspective on Dynamics of Chromatin Compartments
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DOI: 10.3389/fmolb.2021.781981
Abstract: The interior of the eukaryotic cell nucleus has a crowded and heterogeneous environment packed with chromatin polymers, regulatory proteins, and RNA molecules. Chromatin polymer, assisted by epigenetic modifications, protein and RNA binders, forms multi-scale compartments… read more here.
Keywords: chromatin compartments; dynamics chromatin; perspective dynamics; liquid state ... See more keywords
Interplay and Dynamics of Chromatin Architecture and DNA Damage Response: An Overview
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DOI: 10.3390/cancers17060949
Abstract: Simple Summary This review explores the intricate relationship between DNA double-strand break (DSB) repair and chromatin architecture, examining how chromatin influences DSB repair at multiple levels, from histone modifications to nuclear organization, while highlighting the… read more here.
Keywords: chromatin architecture; interplay dynamics; architecture dna; dynamics chromatin ... See more keywords