Preprotein Conformational Dynamics Drive Bivalent Translocase Docking and Secretion.
Sign Up to like & getrecommendations! Published in 2017 at "Structure"
DOI: 10.1016/j.str.2017.05.012
Abstract: Most bacterial secretory proteins destined beyond the plasma membrane are secreted post-translationally by the Sec translocase. In the first step of translocation, preproteins are targeted for binding to their 2-site receptor SecA, the peripheral ATPase… read more here.
Keywords: secretion; translocase; conformational dynamics; preprotein conformational ... See more keywords
Intrinsic nonlinear dynamics drive single-species systems
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2209601119
Abstract: The importance of oscillations and deterministic chaos in natural biological systems has been discussed for several decades and was originally based on discrete-time population growth models (May 1974). Recently, all types of nonlinear dynamics were… read more here.
Keywords: single species; intrinsic nonlinear; drive single; species systems ... See more keywords
Atmospheric dynamics drive most interannual U.S. droughts over the last millennium
Sign Up to like & getrecommendations! Published in 2020 at "Science Advances"
DOI: 10.1126/sciadv.aay7268
Abstract: U.S. drought is analyzed over the past millennium, showing that ENSO has some influence but much variability remains unexplained. The American West exemplifies drought-sensitive regions with growing populations. Paleoclimate investigations have documented severe droughts in… read more here.
Keywords: millennium; drought; last millennium; variability ... See more keywords
Tuning site-specific dynamics to drive allosteric activation in a pneumococcal zinc uptake regulator
Sign Up to like & getrecommendations! Published in 2018 at "eLife"
DOI: 10.7554/elife.37268
Abstract: MarR (multiple antibiotic resistance repressor) family proteins are bacterial repressors that regulate transcription in response to a wide range of chemical signals. Although specific features of MarR family function have been described, the role of… read more here.
Keywords: site specific; tuning site; specific dynamics; activation ... See more keywords