Multiscale Evolutionary Dynamics of Host-Associated Microbiomes
Sign Up to like & getrecommendations! Published in 2018 at "Cell"
DOI: 10.1016/j.cell.2018.02.015
Abstract: The composite members of the microbiota face a range of selective pressures and must adapt to persist in the host. We highlight recent work characterizing the evolution and transfer of genetic information across nested scales of… read more here.
Keywords: multiscale evolutionary; host; associated microbiomes; host associated ... See more keywords
Affinity-Directed Dynamics of Host-Guest Motifs for Pharmacokinetic Modulation via Supramolecular PEGylation.
Sign Up to like & getrecommendations! Published in 2021 at "Biomacromolecules"
DOI: 10.1021/acs.biomac.1c00648
Abstract: Proteins are an impactful class of therapeutics but can exhibit suboptimal therapeutic performance, arising from poor control over the timescale of clearance. Covalent PEGylation is one established strategy to extend circulation time but often at… read more here.
Keywords: pegylation; host guest; supramolecular pegylation; directed dynamics ... See more keywords
Major Insights in Dynamics of Host Response to SARS-CoV-2: Impacts and Challenges
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2021.637554
Abstract: The coronavirus disease 2019 (COVID-19), a pandemic declared by the World Health Organization on March 11, 2020, is caused by the infection of highly transmissible species of a novel coronavirus called severe acute respiratory syndrome… read more here.
Keywords: sars cov; dynamics host; response sars; host response ... See more keywords