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Published in 2023 at "Journal of cellular biochemistry"
DOI: 10.1002/jcb.30410
Abstract: Lipases have been established as important biocatalysts in several industrial applications, owing to their diverse substrate specificity. The availability of data on three-dimensional crystal structures for various lipases offers an opportunity for modulating their structural…
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Keywords:
dynamics mechanistic;
active site;
site;
engineering ... See more keywords
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Published in 2019 at "Journal of chemical information and modeling"
DOI: 10.1021/acs.jcim.9b00588
Abstract: NPAC is a cytokine-like nuclear factor involved in chromatin modification and regulation of gene expression. In humans, the C-terminal domain of NPAC has the conserved structure of the β-hydroxyacid dehydrogenases (β-HAD) protein superfamily, which forms…
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Keywords:
structural dynamics;
mutations npac;
npac structural;
dynamics mechanistic ... See more keywords