Nickel induces hepatotoxicity by mitochondrial biogenesis, mitochondrial dynamics, and mitophagy dysfunction
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DOI: 10.1002/tox.23758
Abstract: Nickel (Ni) is an important and widely hazardous chemical industrial waste. Excessive Ni exposure could cause multi‐organs toxicity in human and animals. Liver is the major target organ of Ni accumulation and toxicity, however, the… read more here.
Keywords: nickel; biogenesis mitochondrial; mitochondrial biogenesis; biogenesis ... See more keywords
Prostaglandin F2α regulates mitochondrial dynamics and mitophagy in the bovine corpus luteum
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DOI: 10.26508/lsa.202301968
Abstract: This study investigates the early effects of PGF2α signaling on mitochondrial dynamics and mitophagy in bovine corpora lutea. Luteolytic mediator PGF2α, via PKC/ERK and AMPK signaling, activates mitochondrial fission and promotes PINK–Parkin mitophagy, placing mitochondria… read more here.
Keywords: prostaglandin regulates; mitochondrial dynamics; regulates mitochondrial; dynamics mitophagy ... See more keywords
Mitochondrial Dynamics and Mitophagy in Cardiometabolic Disease
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Cardiovascular Medicine"
DOI: 10.3389/fcvm.2022.917135
Abstract: Mitochondria play a key role in cellular metabolism. Mitochondrial dynamics (fusion and fission) and mitophagy, are critical to mitochondrial function. Fusion allows organelles to share metabolites, proteins, and mitochondrial DNA, promoting complementarity between damaged mitochondria.… read more here.
Keywords: mitophagy cardiometabolic; mitochondrial dynamics; dynamics mitophagy; cardiometabolic disease ... See more keywords
Excessive Endoplasmic Reticulum Stress Correlates with Impaired Mitochondrial Dynamics, Mitophagy and Apoptosis, in Liver and Adipose Tissue, but Not in Muscles in EMS Horses
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DOI: 10.3390/ijms19010165
Abstract: Nowadays, endocrine disorders have become more frequent in both human and veterinary medicine. In horses, reduced physical activity combined with carbohydrate and sugar overload may result in the development of the so-called equine metabolic syndrome… read more here.
Keywords: apoptosis; liver adipose; tissue; adipose tissue ... See more keywords