Histone acetylation dynamics modulates chromatin conformation and allele-specific interactions at oncogenic loci.
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DOI: 10.1038/s41588-021-00842-x
Abstract: In cancer cells, enhancer hijacking mediated by chromosomal alterations and/or increased deposition of acetylated histone H3 lysine 27 (H3K27ac) can support oncogene expression. However, how the chromatin conformation of enhancer-promoter interactions is affected by these… read more here.
Keywords: dynamics modulates; expression; allele specific; chromatin conformation ... See more keywords